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Virulence: An Infectious Card Game
Family Night Choice

Virulence: An Infectious Card Game

Designed by John Coveyou, Paul Salomon

Published by Genius Games, Ediciones MasQueOca

Casual Flow: 15 Min Teach

Players

2-5

Community Snapshot

Best with 4–5
Medium-Light complexity
10–20 min
6.6 on BGG (354)

Language Editions

EnglishSpanish

Categories

Bluffing
Deceive your opponents — hide your intentions, make false claims, and read others.
Deduction
Use logic and clues to figure out hidden information — who, what, or where.
Dice
Dice rolling is a core mechanism — outcomes depend partly on luck.
Medical
Themes around medicine, healthcare, or the human body.
Number
Numbers are the core component — sequencing, arithmetic, or number theory.

How It Plays

Auction / Bidding

Players bid against each other for cards, tiles, or resources — knowing when to go big and when to fold is the key.

Betting and Bluffing

You place bets and try to read (or mislead) your opponents — poker vibes at the game table!

Deck, Bag, and Pool Building

You start with a basic set of cards or tokens and gradually add better ones — watch your engine grow stronger over time.

Dice Rolling

You roll dice to determine outcomes — there's always that thrilling moment of suspense before they land!

Hand Management

You have a hand of cards and deciding which to play, save, or discard is the core puzzle.

Push Your Luck

You keep rolling or drawing for bigger rewards, but push too far and you lose it all — knowing when to stop is the real skill.

Set Collection

You're gathering matching groups of cards or tokens to score points — the more complete your sets, the better you do.

Simultaneous Action Selection

About This Game

Virulence: An Infectious Card Game is an addictively quick and simple card game focused on viruses infecting a host cell - and how they assemble and replicate inside that host cell. Virulence has players take on the role of viruses competing to infect a host cell in order to replicate their own viral components, thus scoring points. Each round, players secretly choose one Virus card from their hand, place it face down on the table, then simultaneously flip these Virus cards to reveal each player's (and thus each virus') virulence.…

Source: BoardGameGeek

View on BoardGameGeek

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Collections

Featured In

🧒Best Board Games for Kids⏱️Best Board Games Under 60 Minutes🌱Light board games for 2 players🌱Light board games for 3 players🌱Light board games for 4 players

Play Time

10-20 min

Complexity

1.6 / 5

Rating

6.6

Year

2016

Everyone chooses their action at the same time and reveals together — no waiting around, and plenty of surprises.

Variable Player Powers

Each player has unique abilities that make their experience different — finding the best way to use yours is half the fun.